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PATIENT:
CHART NUMBER:
DATE:
REFERRING PHYSICIAN:
FURLONG, NEILA
465-86-8819
7/19/01
DANIEL KRAMPITZ, M.D.
MRI OF THE BRAIN:

CLINICAL HISTORY:  Headaches, difficulty speaking and swallowing and possibley recent seizure.  The patient gives a history of non-small cell carcinoma of the lung with brain metastases and apparently has undergone previous gamma knife surgery.

TECHNIQUE:  T1-weighted images were obtained in the sagittal and axial planes.  FLAIR and T2-weighted axial images were obtained along with a gradient echo coronal sequence and a diffusion sequence.  Contrast was not administered.

COMPARISON:  None.


FINDINGS:

 1. There is diffuse prominence of the ventricles and extra-axial spaces greater than expected for the patient's age.  There is markedly extensive T2 signal abnormality within the white matter of both cerebral hemispheres.  This may be related to previous radiation and/or chemotherapy.  More focal low attenuation is present in the left anterior frontal lobe and there is a small focus of susceptibility artifact in the subcortical region of the left frontal lobe, which may reflect minimal blood products or calcification.  Contrast was unfortunately not administered.  I do not see obvious evidence of mass effect.  No subdural or epidural hematoma is detected.  
2. Diffusion imaging does not reveal evidence of an acute infarct.  No shift of midline structures is evident.  There is no focal mass effect of the ventricles.  There are some prominent perivascular spaces incidentally noted. 
3.  There are normal flow voids within the major intracranial vessels.  Note is made of a partially empty sella.  The visualized sinuses are grossly clear.  There is fluid or inflammatory debris within the mastoid air cells on the left. 

IMPRESSION:
1. Extensive T2 signal abnormality involving the white matter of both cerebral hemispheres which may reflect a sequela of radiation and/or chemotherapy.  Hypertension and/or microvascular ischemic change may contribute.  Small focus of susceptibility artifact in the left frontal lobe may reflect some minimal blood products or clacification.  Perhaps this is the region where previous gamma surgery has been performed.  No obvious mass effect is evident.  Unfortunately, contrast was not administered.  There is more prominent low-signal intensity on T1-weighted images within the left frontal lobe adjacent to this area of susceptibility artifact.
2. No evidence of acute infarct on difficusion imaging.
3. Diffuse prominence to the ventricles and extra-axial spaces should reflect atrophy.

Ellis F. Robertson, M.D.
EFT/clm
D: 7/20/01 8:54AM
T: 7/20/01 8:56AM
Dan Kramptiz, M.D.


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